Otto-von-Guericke-Universität Magdeburg

Institute of Cognitive Neurology and Dementia Research
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MRT       IMG_Foto Forschung

The research area of the IKND focuses on mechamisms of higher cognitive brain functions (as memory, motivation, decision making and behavioral control). Especially researching the disorders of these brain functions in aged persons or in neurodegenerative diseases as dementia syndrom and the Parkinson's dosease is a main focus of the IKND.

Memory functions are effected very early in dementia. In Alzheimer type dementia, the episodic memory, that is the ability to store personal experiences, is reduced in quite early states already. Slight impairments of episodic memory, though, are also frequently found in healthy elderly people. 
The functional imaging by nuclear magnetic tomography (fMRI) as well as electrical recordings (EEG)  in recent years provided new insights in the neuroanatomical organizationof these memory functions, that have direct relevance for the development of preventive and therapeutic strategies for dementia. Neurotransmitters like dopamine, noradrenaline and acetylcholine are of special relevance here. They are not only important for the regulation of higher brain functions, but are also very sensitive to neurodegenerative processes. At the IKND we investigate, by functional and structural imaging as well as analysis of genetic variations, how these transmitters regulate memory functions, and which effects disturbances in these systems have. 
Last Modification: 21.07.2015 - Contact Person: Webmaster